Diseases, Free Full-Text
Por um escritor misterioso
Last updated 27 junho 2024
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Colorectal cancer (CRC) is the third most common cancer worldwide. A diagnosis at early stages with enhanced screening methods is vital as metastases and recurrences increase mortality. The aim of this study was to analyze the tumor markers CEA and CA19-9 combined in correlation with diagnostics and prognosis. Therefore, 1487 patients with CRC who were diagnosed and treated between 2000 and 2015 at the University Hospital Ulm, Germany, were retrospectively evaluated. Overall and recurrence-free survival was analyzed in association with preoperative CEA and CA19-9 separately and combined and a multivariate analysis was performed. The 5-year overall survival was significantly shorter in patients with a CEA or CA19-9 level ≥200 compared to patients with an increased, but <200, or normal level (CEA: 69%/44%/7%; CA19-9: 66%/38%/8%). Patients with both tumor markers increased also showed a remarkably shorter 5-year survival rate (CEA+/CA19-9+: 23%). The multivariate analysis emphasizes these results (p-value < 0.0001). Patients with both tumor markers elevated had the shortest 5-year recurrence-free survival rate, followed by patients with either CEA or CA19-9 elevated (CEA-/CA19-9-: 79%; CEA+/CA19-9; CEA-/CA19-9+: 65%; CEA+/CA19-9+: 44%). In conclusion, measuring CEA and CA19-9 preoperatively in CRC patients is reasonable and could be useful as a prognostic factor.
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Frontiers Management and Prevention Strategies for Non-communicable Diseases (NCDs) and Their Risk Factors
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Global Effect of Modifiable Risk Factors on Cardiovascular Disease and Mortality
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Management of Huanglongbing (HLB) by an Intensive Vector and Disease Control in the Surroundings of the Orchard, in Addition to Planting HLB-Free Trees in Okinawa, Japan
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Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019: Update From the GBD 2019 Study - ScienceDirect
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Report: Healthy Fossil Fuel Free World Means Re-Imagining New Clean Energy Future - The Global Climate and Health Alliance
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Childhood diseases
Infectious Diseases of Poverty
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Physical Activity and Nutrition
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Buy Eat So What! The Power of Vegetarianism Volume 1 (Full Color Print): Nutrition Guide For Weight Loss, Disease Free, Drug Free, Healthy Long Life Book Online at Low Prices in India
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Non-communicable Diseases - Types and Prevention
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Systematic genetic analysis of the MHC region reveals mechanistic underpinnings of HLA type associations with disease
![Diseases, Free Full-Text](https://wwwnc.cdc.gov/eid/images/og-eid-logo-2.jpg)
Emerging Infectious Diseases - CDC
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