A) Generation of mice with loxP-flanked target genes (flox). (1

LoxP-FRT Trap (LOFT): a simple and flexible system for conventional and reversible gene targeting, BMC Biology

One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering - ScienceDirect

Introduction of loxP sites by electroporation in the mouse genome; a simple approach for conditional allele generation in complex targeting loci, BMC Biotechnology

JCI Insight - Fibroblast-specific deletion of IL-1 receptor-1 reduces adverse cardiac remodeling following myocardial infarction

How does Cre/loxP recombination work? - InVivo Biosystems

Flox Sequence Creation and Its Role in Genetic Manipulation

Testing the Cre-mediated genetic switch for the generation of conditional knock-in mice

Generation of a Matrix Gla (Mgp) floxed mouse, followed by conditional knockout, uncovers a new Mgp function in the eye

Cre-Lox Recombination - An Overview

JCI Insight - Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis

Conditional Ablation of the Neural Cell Adhesion Molecule Reduces Precision of Spatial Learning, Long-Term Potentiation, and Depression in the CA1 Subfield of Mouse Hippocampus